Genetic Engineering

 
13.1 Genetic Engineering
 
Introduction to Genetic Engineering
  • Genetic engineering is a gene manipulation technique to genetically modify an organism to form new gene combinations.
  • Organisms whether animals, plants or microorganisms produced through recombinant DNA technology are known as genetically modified organisms or genetically modified organisms (GMOs).
  • Genetic engineering involves the transfer of DNA segments from one organism to another through recombinant DNA technology.
  • By using techniques and procedures in recombinant DNA technology, biologists can reconstruct the DNA or genome (a complete set of DNA) of an organism.
 
Genetically Modified Organism (GMO)
  • Genetically modified organisms (GMOs) are organisms that contain recombinant DNA.
  • Through recombinant DNA technology, new combinations of genes are produced in an organism.
  • Organisms that contain recombinant DNA are known as transgenic organisms.
  • Example of enetically modified organisms (GMOs):
    • Genetically modified cow produces milk which does not contain β-lactoglobulin, a type of protein that causes allergy among some children.
    • Genetically modified goat possesses the human gene which codes for a blood clotting factor. This blood coagulation factor is found in the goat’s milk and can be purified and used to treat haemophilic patients.
 
Genetically Modified Food (GMF)
  • Recombinant DNA technology has successfully produced many crops (rice, oil palm, pineapple, corn and soybeans) as well as livestock (salmon, cattle and goats) that have the desired characteristics.
  • Genetically modified foods (GMF) have DNA from other plant or animal species.
  • Intake of GMF by humans is likely to have a variety of still unknown health implications.
 
This image is an infographic titled ‘CHARACTERISTICS OF GENETICALLY MODIFIED FOOD (GMF).’ It is designed with a light bulb icon in the center, symbolizing ideas or innovations. Around the light bulb, there are five characteristics of GMF, each within its own box and connected by arrows in a circular flow. The characteristics are: 1. Resistant to herbicide. 2. Resistant to disease. 3. Application in medicine. 4. Tolerance to heavy metals. 5. Resistance to pest. The infographic uses a light color palette, primarily blue and orange. The Pandai logo is at the top left corner.
 
Advantages and Disadvantages of GMF
Advantages of GMF
  • Overcome worldwide food shortage by producing high quality transgenic crops amd livestock.
  • Reduce cost of food production.
  • Increase nutritional value of crops.
  • Reduce problems of crops related to pests.
  • Reduce usage of pesticides.
  • Increase in production reduces price of food,thus increase food availabilty.
Disadvantages of GMF
  • Endangered natural species.
  • There is a slight possibility that the foreign gene in GMF may be transferred to humans,for example, antibiotic-resistance gene.
  • May have adverse effects on human health and genetic material.
 
Examples of GMF
Corn
  • A Bacillus thuringiensis gene is inserted into corn to increase its resistance against insect pest.
'Super Salmon'
  • 'Super Salmon' is a genetically modified fish which is approved by the Food and Drug Administration (FDA) as a safe food for consumption in United States of America and Canada.
  • It is modified by inserting a growth hormone gene from a Chinook salmon into the genome of an Atlantic salmon.
  • Hence, a Super Salmon is created which grows at a faster rate and can be produced throughout the year.
 
Insulin
  • The hormone insulin plays an important role in controlling blood sugar levels.
  • In the past, insulin was extracted from the pancreas of cattle or pigs to treat patients with diabetes mellitus.
  • Now, insulin can be obtained from genetic engineering techniques and can be produced commercially for the use of diabetics
  • In addition to insulin, hepatitis B vaccine, blood clotting factors and growth hormone have been successfully genetically engineered.
 

 

 

 

 

Genetic Engineering

 
13.1 Genetic Engineering
 
Introduction to Genetic Engineering
  • Genetic engineering is a gene manipulation technique to genetically modify an organism to form new gene combinations.
  • Organisms whether animals, plants or microorganisms produced through recombinant DNA technology are known as genetically modified organisms or genetically modified organisms (GMOs).
  • Genetic engineering involves the transfer of DNA segments from one organism to another through recombinant DNA technology.
  • By using techniques and procedures in recombinant DNA technology, biologists can reconstruct the DNA or genome (a complete set of DNA) of an organism.
 
Genetically Modified Organism (GMO)
  • Genetically modified organisms (GMOs) are organisms that contain recombinant DNA.
  • Through recombinant DNA technology, new combinations of genes are produced in an organism.
  • Organisms that contain recombinant DNA are known as transgenic organisms.
  • Example of enetically modified organisms (GMOs):
    • Genetically modified cow produces milk which does not contain β-lactoglobulin, a type of protein that causes allergy among some children.
    • Genetically modified goat possesses the human gene which codes for a blood clotting factor. This blood coagulation factor is found in the goat’s milk and can be purified and used to treat haemophilic patients.
 
Genetically Modified Food (GMF)
  • Recombinant DNA technology has successfully produced many crops (rice, oil palm, pineapple, corn and soybeans) as well as livestock (salmon, cattle and goats) that have the desired characteristics.
  • Genetically modified foods (GMF) have DNA from other plant or animal species.
  • Intake of GMF by humans is likely to have a variety of still unknown health implications.
 
This image is an infographic titled ‘CHARACTERISTICS OF GENETICALLY MODIFIED FOOD (GMF).’ It is designed with a light bulb icon in the center, symbolizing ideas or innovations. Around the light bulb, there are five characteristics of GMF, each within its own box and connected by arrows in a circular flow. The characteristics are: 1. Resistant to herbicide. 2. Resistant to disease. 3. Application in medicine. 4. Tolerance to heavy metals. 5. Resistance to pest. The infographic uses a light color palette, primarily blue and orange. The Pandai logo is at the top left corner.
 
Advantages and Disadvantages of GMF
Advantages of GMF
  • Overcome worldwide food shortage by producing high quality transgenic crops amd livestock.
  • Reduce cost of food production.
  • Increase nutritional value of crops.
  • Reduce problems of crops related to pests.
  • Reduce usage of pesticides.
  • Increase in production reduces price of food,thus increase food availabilty.
Disadvantages of GMF
  • Endangered natural species.
  • There is a slight possibility that the foreign gene in GMF may be transferred to humans,for example, antibiotic-resistance gene.
  • May have adverse effects on human health and genetic material.
 
Examples of GMF
Corn
  • A Bacillus thuringiensis gene is inserted into corn to increase its resistance against insect pest.
'Super Salmon'
  • 'Super Salmon' is a genetically modified fish which is approved by the Food and Drug Administration (FDA) as a safe food for consumption in United States of America and Canada.
  • It is modified by inserting a growth hormone gene from a Chinook salmon into the genome of an Atlantic salmon.
  • Hence, a Super Salmon is created which grows at a faster rate and can be produced throughout the year.
 
Insulin
  • The hormone insulin plays an important role in controlling blood sugar levels.
  • In the past, insulin was extracted from the pancreas of cattle or pigs to treat patients with diabetes mellitus.
  • Now, insulin can be obtained from genetic engineering techniques and can be produced commercially for the use of diabetics
  • In addition to insulin, hepatitis B vaccine, blood clotting factors and growth hormone have been successfully genetically engineered.
 

 

 

 

 

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